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Seeing the Future of Brain Health Through the Eyes

The Eye ACT study aims to provide insights on how ophthalmic conditions such as macular degeneration and diabetic retinopathy can provide early clues to Alzheimer’s disease. By understanding the connection between the eyes and brain, we aim to drive advancements in early detection and prevention of neurodegenerative diseases.

How the Eye ACT Study Stands Out

Detailed Data Collection

Integrating Eye and Brain Health Insights

Eye ACT combines advanced imaging, genetic data, and clinical evaluations to uncover the connection between retinal changes and neurodegenerative processes. By analyzing ophthalmic data with Alzheimer’s risk factors, the study offers actionable insights for early intervention.

Long-Term Follow-Up

Revealing Retinal Health Trends Over Time

With ongoing monitoring, Eye ACT tracks how retinal biomarkers evolve alongside cognitive decline. This long-term approach offers unique insights into how eye health may predict brain health changes, advancing Alzheimer’s detection strategies.

Rigorous Analytical Methods

Innovative Non-Invasive Diagnostic Tools

Using imaging technologies and statistical analysis, Eye ACT identifies retinal biomarkers that align with Alzheimer’s risk. These non-invasive methods are transforming early detection and paving the way for personalized care.

Snapshot of the Eye ACT project

Project Milestones

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Data collected

Shaping the Future of Alzheimer's Detection and Care

Our study analyzes data from over 3,877 participants aged 65 and older, enrolled through Kaiser Permanente Washington. With 31,142 person-years of follow-up, we assessed cognitive decline and Alzheimer's risk in relation to eye conditions.

Revolutionizing Alzheimer's Research Through Ophthalmology

Our research shows how changes in the retina mirror neurodegenerative processes provide an accessible window into brain health. By identifying retinal biomarkers, we're creating tools for non-invasive Alzheimer's risk assessment.

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Eye ACT Members

The following organizations are part of the Eye ACT project

Retinal Imaging

Exploring Retinal Changes for Brain Health Insights

The Eye ACT study goes beyond traditional approaches by exploring how subtle retinal changes can provide a dynamic view of brain health over time. These insights are shaping how we detect and understand neurodegenerative conditions.

Bridging Retinal and Cognitive Health

Eye ACT uniquely correlates retinal imaging findings with cognitive decline, providing a clearer picture of Alzheimer’s progression and opening avenues for targeted intervention strategies.