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Seeing the Future of Brain Health Through the Eyes

The Eye ACT study aims to provide insights on how ophthalmic conditions such as glaucoma and diabetic retinopathy can provide early clues to Alzheimer’s disease. By understanding the connection between the eyes and brain, we aim to drive advancements in early detection and prevention of neurodegenerative diseases.

How the EyeACT Study Stands Out

Detailed Data Collection

Integrating Eye and Brain Health Insights

EyeACT combines advanced imaging, genetic data, and clinical evaluations to uncover the connection between retinal changes and neurodegenerative processes. By analyzing ophthalmic data with Alzheimer’s risk factors, the study offers actionable insights for early intervention.

Long-Term Follow-Up

Revealing Retinal Health Trends Over Time

With ongoing monitoring, EyeACT tracks how retinal biomarkers evolve alongside cognitive decline. This long-term approach offers unique insights into how eye health may predict brain health changes, advancing Alzheimer’s detection strategies.

Rigorous Analytical Methods

Innovative Non-Invasive Diagnostic Tools

Using imaging technologies and statistical analysis, EyeACT identifies retinal biomarkers that align with Alzheimer’s risk. These non-invasive methods are transforming early detection and paving the way for personalized care.

Snapshot of the Eye ACT project

Project Milestones

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Advancing Research at the Intersection of Eye Health and Alzheimer’s Disease

EyeACT leverages advances in retinal imaging and data analysis to bridge the gap between eye health and Alzheimer’s research. Our focus is on translating these findings into actionable tools for early detection and treatment, paving the way for personalized care.

Revolutionizing Retinal Imaging

Revolutionizing Retinal Imaging

Our research utilizes advanced imaging techniques such as OCT and OCTA to detect early retinal changes. These insights provide a clearer understanding of the relationship between retinal health and Alzheimer’s disease progression.

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Innovative Detection Strategies

Innovative Detection Strategies

By identifying key retinal biomarkers, EyeACT is pioneering tools that predict Alzheimer’s risk years before clinical symptoms emerge, offering a unique approach to early detection.

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Transforming Patient Care

Transforming Patient Care

EyeACT integrates eye and brain research to inform targeted interventions for Alzheimer’s. These breakthroughs are shaping personalized treatments to improve patient outcomes.

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Shaping the Future of Alzheimer’s Detection and Care

Our study analyzes data from over 3,877 participants aged 65 and older, enrolled through Kaiser Permanente Washington. With 31,142 person-years of follow-up, we assessed cognitive decline and Alzheimer's risk in relation to eye conditions.

Retinal Imaging

Exploring Retinal Changes for Brain Health Insights

The EyeACT study goes beyond traditional approaches by exploring how subtle retinal changes can provide a dynamic view of brain health over time. These insights are shaping how we detect and understand neurodegenerative conditions.

Bridging Retinal and Cognitive Health

EyeACT uniquely correlates retinal imaging findings with cognitive decline, providing a clearer picture of Alzheimer’s progression and opening avenues for targeted intervention strategies.

Revolutionizing Alzheimer’s Research Through Ophthalmology

Our research shows how changes in the retina mirror neurodegenerative processes provide an accessible window into brain health. By identifying retinal biomarkers, we’re creating tools for non-invasive Alzheimer’s risk assessment.

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